6-溴-4-羟基喹啉-3-甲酸合成路线 （共 7 条）
反应条件
sodium hydroxide 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 22 p. 6443 - 6450
反应条件
1: various solvent(s) / 1 h / Heating 2: aq. NaOH / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 22 p. 6443 - 6450
反应条件
1: 1 h / Heating 2: various solvent(s) / 1 h / Heating 3: aq. NaOH / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 22 p. 6443 - 6450
反应条件
1: diphenyl ether 2: acetic acid; bromine View Scheme
参考文献
Schofield; Swain
Journal of the Chemical Society, 1950 , p. 384,389
反应条件
1: diphenyl ether 2: phosphoryl chloride / 135 °C View Scheme
参考文献
INTELLIKINE, LLC; REN, Pingda; LIU, Yi; LI, Liansheng; CHAN, Katrina; WILSON, Troy, Edward; CAMPBELL, Simon, Fraser
Patent: WO2012/116237 A2, 2012 ;
WO 2012/116237 A2
反应条件
in diphenylether 9 h; Heating / reflux;
参考文献
Chen, Li; Chen, Shaoqing; Lou, Jianping; Sidduri, Achyutharao
Patent: US2006/63805 A1, 2006 ;
Location in patent: Page/Page column 9 ;
US 20060063805 A1
反应条件
1: diphenyl ether
2: acetic acid; acetic acid anhydride; sulfuryl chloride
View Scheme
参考文献
Schofield; Swain
Journal of the Chemical Society, 1950 , p. 384,389
