2-苄基磺酰基-[1,2,4]噻唑并[1,5-a]嘧啶-5,7-二醇合成路线 (共 3 条)
反应条件
sodium methylate in methanol; ethanol; water
参考文献
THE DOW CHEMICAL COMPANY
Patent: EP142152 B1, 1991 ;
反应条件
1: With sodium methylate in methanol; ethanol
120 h; Reflux;
2: With hydrogenchloride; water
参考文献
Chen, Chao-Nan; Lv, Li-Li; Ji, Feng-Qin; Chen, Qiong; Xu, Hui; Niu, Cong-Wei; Xi, Zhen; Yang, Guang-Fu
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 8 p. 3011 - 3017
反应条件
1.) NaOPr
1.) n-PrOH, 5 min, 2.) n-PrOH, from 104 to 108 deg C, 5 h; Yield given. Multistep reaction;
参考文献
McKendry
Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 3 p. 231 - 240