2-碘-1-甲氧基-3-硝基苯合成路线 （共 6 条）
反应条件
1.1: 60 percent / Fe; AcOH / ethanol / 3.5 h / Heating 2.1: NaHCO3; HCO2Na; n-Bu4NCl / Pd(OAc)2; NaCl / 1 h 2.2: 58 percent / Ac2O / 12 h / Heating View Scheme
参考文献
Tullberg, Erik; Schacher, Felix; Peters, Dan; Frejd, Torbjoern
Synthesis, 2006 , # 7 p. 1183 - 1189
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
Tullberg, Erik; Schacher, Felix; Peters, Dan; Frejd, Torbjoern
Synthesis, 2006 , # 7 p. 1183 - 1189
反应条件
1.1: sulfuric acid / water; dimethyl sulfoxide / 2 h / 50 °C
1.2: 1.08 h / 0 °C
1.3: 2 h / 0 - 20 °C
2.1: potassium carbonate / N,N-dimethyl-formamide
View Scheme
参考文献
Yepremyan, Akop; Minehan, Thomas G.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 27 p. 5194 - 5196
参考文献
Baker et al.
Journal of the Chemical Society, 1958 , p. 2658,2662
反应条件
1: 1.) Hg(OAc)2, 2.) KI, I2 / 1.) H2O, 100 deg C, 0.5 h, 2.) H2O, RT, 3 h
2: KOH
View Scheme
参考文献
Cereghetti, Marco; Schmid, Rudolf; Schoenholzer, Peter; Rageot, Alain
Tetrahedron Letters, 1996 , vol. 37, # 30 p. 5343 - 5346
反应条件
iron(III) chloride; hydrazine hydrate in methanol
47 h; Heating;
参考文献
Hine, Jack; Hahn, Soonkap; Miles, David E.; Ahn, Kyunghye
Journal of Organic Chemistry, 1985 , vol. 50, # 25 p. 5092 - 5096
