2-氨基-4-硝基甲苯合成路线 （共 108 条）
反应条件
1: glacial acetic acid; sodium nitrite / durch Diazotieren 2: aqueous-alcoholic KOH-solution View Scheme
参考文献
Noelting
Chemische Berichte, 1904 , vol. 37, p. 2583
反应条件
acetic acid Condensation; 5 h; Heating;
参考文献
Vamecq, Joseph; Bac, Pierre; Herrenknecht, Christine; Maurois, Pierre; Delcourt, Philippe; Stables, James P.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1311 - 1319
反应条件
trichlorophosphate 2 h; heated on a steam bath;
参考文献
Bergman, Jan; Sand, Peter
Tetrahedron, 1990 , vol. 46, # 17 p. 6085 - 6112
反应条件
sulfuric acid Diazotization.anschliessend Behandeln mit Cu2O in wss. NH3;
参考文献
Albert; Linnell
Journal of the Society of Chemical Industry, London, 1936 , vol. 55, p. 54 T
参考文献
Owen, Stephen; Otani, Takahito; Masaoka, Satoshi; Ohe, Tatsuhiko
Bioscience, Biotechnology and Biochemistry, 1996 , vol. 60, # 2 p. 244 - 248
参考文献
Vittenet
Bulletin de la Societe Chimique de France, 1899 , vol. <3>21, p. 588
反应条件
1: HNO3 / ethanol / Heating 2: NaOH / propan-2-ol / 24 h / Heating 3: 8.9 g / SnCl2; aq. HCl / 0.5 h 4: 61 percent / dimethylformamide / 2 h / 0 °C 5: 68 percent / acetonitrile / 6 h / Heating View Scheme
参考文献
IND-SWIFT LABORATORIES LIMITED; AGGARWAL, Ashvin, Kumar; JAIN, Anshul, Kumar; BHIRUD, Shekhar, Bhaskar; WADHWA, Lalit
Patent: WO2011/39782 A1, 2011 ;
参考文献
Maier, Jennifer A.; Brugel, Todd A.; Sabat, Mark; Golebiowski, Adam; Laufersweiler, Matthew J.; VanRens, John C.; Hopkins, Corey R.; De, Biswanath; Hsieh, Lily C.; Brown, Kimberly K.; Easwaran, Vijayasurian; Janusz, Michael J.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 14 p. 3646 - 3650
反应条件
1: glacial acetic acid; sodium nitrite / durch Diazotieren View Scheme
参考文献
Witt; Noelting; Grandmougin
Chemische Berichte, 1890 , vol. 23, p. 3642
Chemische Berichte, 1892 , vol. 25, p. 3152
反应条件
1: ice; concentrated hydrochloric acid / mit NaNO2 diazotieren und in CuCl-Loesung giessen 2: permanganate 3: potassium carbonate; copper powder 4: phosphorus pentachloride; benzene / Beim Kochen die erhaltene Loesung mit Aluminiumchlorid View Scheme
参考文献
Ullmann; Wagner
Justus Liebigs Annalen der Chemie, 1907 , vol. 355, p. 366
Justus Liebigs Annalen der Chemie, 1909 , vol. 371, p. 388
