2-氨基-4-硝基苯酚合成路线 （共 142 条）
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium hydrogencarbonate in chloroform T=0 - 60°C;
参考文献
Kelly, Michael G.; Kincaid, John; Janagani, Satyanarayana; Duncton, Matthew
Patent: US2006/205773 A1, 2006 ;
Location in patent: Page/Page column 25 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; [C8mim][BF4] T=20°C; 2.5 h; chemoselective reaction;
参考文献
Sharifi, Ali; Barazandeh, Mehdi; Saeed Abaee; Mirzaei, Mojtaba
Tetrahedron Letters, 2010 , vol. 51, # 14 p. 1852 - 1855
反应条件
sodium hydroxide; triethylamine in tetrahydrofuran; dichloromethane; water; ethyl acetate
参考文献
Rohm and Haas Company
Patent: US5393735 A1, 1995 ;
反应条件
sodium hydrogencarbonate in chloroform; water
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
1: sodium hydrogen carbonate / CHCl3 / 0.2 h / 40 °C / microwave irradiation 2: 96 percent / potassium carbonate / dimethylformamide / 0.25 h / 80 °C / microwave irradiation View Scheme
参考文献
Caliendo, Giuseppe; Grieco, Paolo; Perissutti, Elisa; Santagada, Vincenzo; Santini, Antonello; Albrizio, Stefania; Fattorusso, Caterina; Pinto, Aldo; Sorrentino, Raffaella
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 12 p. 957 - 967
参考文献
Davies,D.I. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 2653 - 2660
反应条件
2: glacial acetic acid; fuming nitric acid 3: concentrated hydrochloric acid / 130 °C View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 205, p. 72
反应条件
potassium carbonate in acetone
参考文献
Shell Oil Company
Patent: US4180572 A1, 1979 ;
反应条件
1: 96 percent / pTsOH / toluene / 100 °C 2: hydrogen / Pd/C / ethanol View Scheme
参考文献
Lecubin, Florence; Benhida, Rachid; Fourrey, Jean-Louis; Sun, Jian-Sheng
Tetrahedron Letters, 1999 , vol. 40, # 46 p. 8085 - 8088
反应条件
in pyridine; chloroform; water; toluene
参考文献
The United States of America as represented by the Department of Health, Education and Welfare
Patent: US4082781 A1, 1978 ;
