2-氨基-4-硝基苯酚合成路线 （共 142 条）
参考文献
Guerkan, Perihan; Guenduez, Necla
Journal of the Indian Chemical Society, 1997 , vol. 74, # 9 p. 713 - 714
反应条件
1: NaNO2, aq. HBF4
2: aq. NaOH, Cu
3: Na2S2O4, aq. NaOH
View Scheme
参考文献
Focella,A. et al.
Canadian Journal of Chemistry, 1972 , vol. 50, p. 2025 - 2030
反应条件
1.1: NaNO2; aq. H2SO4 / dimethylsulfoxide / 0 °C
1.2: KI / dimethylsulfoxide / 20 °C
2.1: 66 percent / CuI / Pd(PPh3)2Cl2 / acetonitrile; toluene / 0.33 h / 20 °C
View Scheme
参考文献
Dai, Wei-Min; Lai, Kwong Wah
Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9377 - 9380
反应条件
1: 2-amino-4-nitro-phenol With hydrogenchloride; sodium nitrite in water
T=0 - 5°C;
2: β-naphthol With sodium hydroxide in methanol; water
T=5°C;
参考文献
Satam, Manjaree A.; Sekar, N.; Raut, Rajesh K.
Dyes and Pigments, 2013 , vol. 96, # 1 p. 92 - 103,12
反应条件
sodium formate
2.5 h; Heating;
参考文献
Foeldenyi; Szalontai; Szebenyi; Kvintovics; Bartik
Monatshefte fur Chemie, 1996 , vol. 127, # 3 p. 305 - 311
反应条件
pyridine
1.) 100 deg C, 1 h; 2.) 200 deg C, 0.5 h; Yield given. Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3168 - 3178
反应条件
1: 1.) pyridine / 1.) 100 deg C, 1 h; 2.) 200 deg C, 0.5 h
2: 77.8 percent / H2 / 10percent Pd-C / ethyl acetate
View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3168 - 3178
反应条件
in methanol
Heating;
参考文献
Lagutkin, N. A.; Mitin, N. I.; Zubairov, M. M.; Zelentsov, V. V.; Nikolaeva, T. B.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 2 p. 113 - 116
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 2 p. 178 - 181
反应条件
potassium carbonate in acetone
Heating;
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, P. Pulla
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 297 - 299
反应条件
1: acetic acid / 2 h / Reflux
2: potassium carbonate / acetone / 3 h / Reflux
3: water; hydrazine / ethanol / 2 h / Reflux
View Scheme
参考文献
Celgene Avilomics Research, Inc.; Tester, Richland; Chaturvedi, Prasoon; Zhu, Zhendong; Surapaneni, Sekhar S.; Beebe, Lisa
Patent: US2014/179720 A1, 2014 ;
