反应条件
1.1: 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane / toluene / 16 h / 40 °C 1.2: 20 h / 20 °C 2.1: triethylamine / dichloromethane / 0 - 20 °C View Scheme
参考文献
Kazmierski, Wieslaw M.; Maynard, Andrew; Duan, Maosheng; Baskaran, Sam; Botyanszki, Janos; Crosby, Renae; Dickerson, Scott; Tallant, Matthew; Grimes, Rick; Hamatake, Robert; Leivers, Martin; Roberts, Christopher D.; Walker, Jill
Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 2058 - 2073