反应条件
1: 98 percent / H2 / Rh/C / tetrahydrofuran / 18 h / 76000 Torr
2: 90 percent / pyridinium chlorochromate; Celite; sodium carbonate / CH2Cl2 / 4 h / 20 °C
3: 90 percent / p-toluenesulfonic acid monohydrate / toluene / 18 h / Heating
4: 95 percent / LiAlH4 / diethyl ether / 3 h / 20 °C
5: 97 percent / oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 2 h / -60 - 20 °C
View Scheme
参考文献
Kitbunnadaj, Ruengwit; Hoffmann, Marcel; Fratantoni, Silvina A.; Bongers, Gerold; Bakker, Remko A.; Wieland, Kerstin; El Jilali, Ahmed; De Esch, Iwan J. P.; Menge, Wiro M. P. B.; Timmerman, Henk; Leurs, Rob
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 23 p. 6309 - 6323