4-(2-甲氧基苯基)-4-氧代丁酸甲酯合成路线 (共 8 条)
反应条件
potassium hydroxide; hydrazine hydrate; diethylene glycol T=200°C; Erwaermen des Reaktionsprodukts mit wss. Natronlauge und Dimethylsulfat;
参考文献
Dauben; Tanabe
Journal of the American Chemical Society, 1949 , vol. 71, p. 2877
反应条件
water; potassium hydroxide in methanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 2 p. 502 - 507
反应条件
1: potassium hydroxide; diethylene glycol; hydrazine hydrate / 200 °C / Erwaermen des Reaktionsprodukts mit wss. Natronlauge und Dimethylsulfat 2: benzene; ethanol View Scheme
参考文献
Dauben; Tanabe
Journal of the American Chemical Society, 1949 , vol. 71, p. 2877
反应条件
potassium carbonate in tetrahydrofuran
参考文献
Zhang, Yong; Jung, Seo Yoon; Jin, Changbae; Kim, Nam Doo; Gong, Ping; Lee, Yong Sup
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 502 - 507
反应条件
diethyl ether; cadmium (II) chloride; benzene
Erwaermen der vom Aether befreiten Reaktionsloesung mit Bernsteinsaeure-methylester-chlorid;
参考文献
Dauben; Tanabe
Journal of the American Chemical Society, 1949 , vol. 71, p. 2877
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Dauben; Tilles
Journal of Organic Chemistry, 1950 , vol. 15, p. 785,787
反应条件
potassium hexamethylsilazane
1.) toluene, THF, -78 deg C, 1 h, 2.) -78 deg C, 1 h; Multistep reaction;
参考文献
Frenette, R.; Monette, M.; Bernstein, M. A.; Young, R. N.; Verhoeven, T. R.
Journal of Organic Chemistry, 1991 , vol. 56, p. 3083 - 3089
反应条件
methanol; mineral acid
参考文献
Trivedi; Nargund
Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1941 , vol. 10/3A, p. 99
Chem.Abstr., 1955 , p. 176
反应条件
1: aq. NaOH solution
2: methanol; mineral acid
View Scheme
参考文献
Trivedi; Nargund
Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1941 , vol. 10/3A, p. 99
Chem.Abstr., 1955 , p. 176