potassium carbonate; cesium fluoride in water; isopropylamine; N,N-dimethyl-formamide

1: (S)-(+)-3-nitro-benzenesulfonic acid oxiranylmethyl ester; 4-(2-isopropoxy-ethoxymethyl)-phenol With potassium carbonate; cesium fluoride in N,N-dimethyl-formamide T=25°C; Etherification; 2: isopropylamine T=5°C; Addition; ring cleavage;

potassium carbonate; cesium fluoride 1.) DMF, 25 deg C, 30 h, 2.) DMF, 50 deg C, 18 h; Yield given. Multistep reaction;