乙基1-乙基-4-氧代-3-哌啶羧酸酯合成路线 （共 6 条）
反应条件
hydrogenchloride Heating;
参考文献
Fujita, Masakazu; Seki, Taketsugu; Inada, Haruaki; Ikeda, Naoko
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 12 p. 1607 - 1611
反应条件
2: Raney nickel; ethanol; NH3 / 150 °C / 147102 Torr / Hydrogenation View Scheme
参考文献
Fuson et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1239
反应条件
sodium hydride in ethanol; toluene
Dieckmann reaction; Heating;
参考文献
Fujita, Masakazu; Seki, Taketsugu; Inada, Haruaki; Ikeda, Naoko
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 12 p. 1607 - 1611
反应条件
1: 84 percent / Et3N / acetonitrile / 80 °C
2: 100 percent / NaH / toluene; ethanol / Heating
View Scheme
参考文献
Fujita, Masakazu; Seki, Taketsugu; Inada, Haruaki; Ikeda, Naoko
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 12 p. 1607 - 1611
反应条件
2: isopropyl alcohol
View Scheme
参考文献
Cardwell; McQuillin
Journal of the Chemical Society, 1949 , p. 708,712
反应条件
2: Raney nickel; ethanol; NH3 / 150 °C / 147102 Torr / Hydrogenation
3: phenol / 160 - 168 °C
View Scheme
参考文献
Fuson et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1239
