7-氨基-2,3-二氢-1,4-苯并二氧杂环己-6-羧酸合成路线 （共 7 条）
反应条件
1: 43 percent / piperidine / ethanol / 24 h / Heating 2: 89 percent / POCl3; N,N-dimethylaniline / 2 h / Heating View Scheme
参考文献
Archiv der Pharmazie, , vol. 334, # 11 p. 357 - 360
反应条件
hydrazine hydrate; palladium on activated charcoal in methanol
参考文献
da Silva, Joaquim Fernando Mendes; Walters, Marcus; Al-Damluji, Saad; Ganellin, C. Robin
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 15 p. 7254 - 7263
反应条件
ethanol; nickel
Hydrogenation;
参考文献
Heertjes et al.
Journal of the Chemical Society, 1957 , p. 3445
反应条件
1: acetyl chloride; aluminium chloride; carbon disulfide
2: alkaline aqueous sodium hypochlorite solution
3: acetic acid; sulfuric acid; nitric acid
4: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Heertjes et al.
Journal of the Chemical Society, 1957 , p. 3445
反应条件
1: alkaline aqueous sodium hypochlorite solution
2: acetic acid; sulfuric acid; nitric acid
3: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Heertjes et al.
Journal of the Chemical Society, 1957 , p. 3445
反应条件
1: acetic acid; sulfuric acid; nitric acid
2: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Heertjes et al.
Journal of the Chemical Society, 1957 , p. 3445
反应条件
piperidine in ethanol
24 h; Heating;
参考文献
Lee, Jae Yeol; Park, Yong Kyu; Seo, Seon Hee; So, In-Seop; Chung, Hee-Kyung; Yang, Beom-Seok; Lee, Sook Ja; Park, Hokoon; Lee, Yong Sup
Archiv der Pharmazie, 2001 , vol. 334, # 11 p. 357 - 360
