N-氯羰基氧基-5-降冰片烯-2,3-二甲酰亚胺合成路线 （共 12 条）
反应条件
1: pyridine / 1.) room temp., 1 h; 2.) 35 deg C, 3 h 2: 87 percent / tertiary amine / H2O; dioxane / 3 h View Scheme
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
反应条件
1: pyridine / 1.) room temp., 1 h; 2.) 35 deg C, 3 h 2: 91 percent / tertiary amine / H2O; dioxane / 3 h View Scheme
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
反应条件
1) THF, -5 deg C, 30 min and 2 h, r.t., 2) DMF, 3 h, r.t.; Yield given. Multistep reaction;
参考文献
Henklein; Jahrling; Teubner; Tietze; Ott
Pharmazie, 1989 , vol. 44, # 3 p. 225 - 226
反应条件
pyridine 1.) room temp., 1 h; 2.) 35 deg C, 3 h;
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
反应条件
1: pyridine / 1.) room temp., 1 h; 2.) 35 deg C, 3 h 2: 85 percent / tertiary amine / H2O; dioxane / 3 h View Scheme
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
反应条件
1: pyridine / 1.) room temp., 1 h; 2.) 35 deg C, 3 h 2: 64 percent / tertiary amine / H2O; dioxane / 3 h View Scheme
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran 1) 0 deg C, 1 h, 2) 3 h, room temperature;
参考文献
Jahrling; Henklen; Schlender; Rackwitz; Niedrich
Pharmazie, 1990 , vol. 45, # 2 p. 138 - 139
反应条件
1: pyridine / 1.) room temp., 1 h; 2.) 35 deg C, 3 h 2: 81 percent / tertiary amine / H2O; dioxane / 3 h View Scheme
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
反应条件
in tetrahydrofuran
T=0°C;
参考文献
Henklein, Peter; Halatsch, Wolf-Rainer; Heyne, Hans-Ulrich
Zeitschrift fuer Chemie (Stuttgart, Germany), 1986 , vol. 26, # 9 p. 329 - 330
反应条件
sodium hydroxide
1.) MeOH; 2.) benzene, 10-15 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut
Synthesis, 1987 , # 2 p. 166 - 167
