1-(苯基磺酰)-1H-吲哚-3-羰酰氯合成路线 （共 7 条）
反应条件
1: CH2Cl2 2: 94 percent / phosphorus oxychloride / benzene / 7 h / Heating 3: 82 percent / K2CO3 / methanol; H2O / 2 h / Heating View Scheme
参考文献
Ketcha, Daniel M.; Gribble, Gordon W.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5451 - 5457
反应条件
thionyl chloride
T=20°C; 3 h;
参考文献
Pouilhes, Annie; Langlois, Yves; Chiaroni, Angele
Synlett, 2003 , # 10 p. 1488 - 1490
反应条件
1.1: BuLi / tetrahydrofuran / 0.5 h / -60 - -40 °C
1.2: 88 percent / tetrahydrofuran / 20 h / -60 - 20 °C
2.1: SOCl2 / 3 h / 20 °C
View Scheme
参考文献
Pouilhes, Annie; Langlois, Yves; Chiaroni, Angele
Synlett, 2003 , # 10 p. 1488 - 1490
反应条件
1.1: BuLi / tetrahydrofuran / 0.5 h / -60 - -40 °C
1.2: 88 percent / tetrahydrofuran / 20 h / -60 - 20 °C
2.1: SOCl2 / 3 h / 20 °C
View Scheme
参考文献
Pouilhes, Annie; Langlois, Yves; Chiaroni, Angele
Synlett, 2003 , # 10 p. 1488 - 1490
反应条件
aluminium trichloride
1) CH2Cl2, 0.5 h, 0 deg C, 2) CH2Cl2, 2 h, r.t.; Yield given. Multistep reaction;
参考文献
Buttery, Cheryl D.; Jones, Richard G.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 13 p. 1425 - 1432
反应条件
sodium hydrogencarbonate
T=20°C;
参考文献
Silvestri, Romano; De Martino, Gabriella; La Regina, Giuseppe; Artico, Marino; Massa, Silvio; Vargiu, Laura; Mura, Massimo; Loi, Anna Giulia; Marceddu, Tiziana; La Colla, Paolo
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2482 - 2493
反应条件
1: CH2Cl2
2: 94 percent / phosphorus oxychloride / benzene / 7 h / Heating
View Scheme
参考文献
Ketcha, Daniel M.; Gribble, Gordon W.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5451 - 5457
