3-乙酰基-6-甲氧基吲哚合成路线 （共 9 条）
反应条件
1: 6-methoxy-1H-indole With diethylaluminium chloride in hexane; dichloromethane T=0°C; 0.5 h; 2: acetyl chloride in hexane; dichloromethane T=50°C; 0.166667 h; microwave irradiation; Further stages.;
参考文献
De Luca, Laura; Barreca, Maria Letizia; Ferro, Stefania; Iraci, Nunzio; Michiels, Martine; Christ, Frauke; Debyser, Zeger; Witvrouw, Myriam; Chimirri, Alba
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 9 p. 2891 - 2895
反应条件
potassium carbonate in methanol; water 2 h; Heating;
参考文献
Ketcha, Daniel M.; Gribble, Gordon W.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5451 - 5457
反应条件
sodium hydroxide in water 4 h; Reflux;
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
反应条件
sodium hydroxide in water 2 h; Reflux;
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
反应条件
1: 1.) AlCl3 / 1.) CH2Cl2, 25 deg C, 15 min, 2.) CH2Cl2, 25 deg C, 2 h 2: 79 percent / K2CO3 / methanol; H2O / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 26 p. 5451 - 5457
反应条件
1: 100 percent / pyridine / CH2Cl2 / 1.) 0 deg C, 1 h, 2.) 25 deg C, overnight 2: 81 percent / BF3*Et2O / CH2Cl2 / 1.5 h / 0 °C 3: 1.) AlCl3 / 1.) CH2Cl2, 25 deg C, 15 min, 2.) CH2Cl2, 25 deg C, 2 h 4: 79 percent / K2CO3 / methanol; H2O / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 26 p. 5451 - 5457
反应条件
1: 81 percent / BF3*Et2O / CH2Cl2 / 1.5 h / 0 °C 2: 1.) AlCl3 / 1.) CH2Cl2, 25 deg C, 15 min, 2.) CH2Cl2, 25 deg C, 2 h 3: 79 percent / K2CO3 / methanol; H2O / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 26 p. 5451 - 5457
反应条件
1: propionic acid anhydride / 100 °C 2: sodium hydroxide / water / 4 h / Reflux View Scheme
参考文献
Letters in Organic Chemistry, , vol. 8, # 9 p. 656 - 662
反应条件
tetrabutylammomium bromide; potassium carbonate in acetonitrile
T=20°C; 0.333333 h;
参考文献
Venkatanarayana, Muvvala; Dubey, Pramod K.
Letters in Organic Chemistry, 2012 , vol. 9, # 3 p. 192 - 197
