1: 100 percent / H2 / 10percent palladized charcoal / acetic acid / 4 h / Ambient temperature 2: sodium amalgam, aq. acetic acid / 18 h / 37 °C / enzymes from Euglena gracilis 3: 1.) 2M aq. potassium hydroxide; 2.) sodium amalgam / 1.) tetrahydrofuran 20 deg C; 2.) 3-4 min 4: 0.5 h / coproporphyrinogen-III oxidase (from Euglena gracilis) View Scheme

1: 100 percent / H2 / 10percent palladized charcoal / acetic acid / 4 h / Ambient temperature 2: sodium amalgam, aq. acetic acid / 18 h / 37 °C / enzymes from Euglena gracilis 3: 1.) 2M aq. potassium hydroxide; 2.) sodium amalgam / 1.) tetrahydrofuran 20 deg C; 2.) 3-4 min View Scheme