N-chloro-succinimide in methanol; acetic acid to a soln. of B-compd. in MeOH was added NaI in MeOH, then Na(125)I was added (100percent stoichiometric amount of NaI/Na(125)I), addn. of AcOH followed by addn. of two equivalents of NCS in MeOH, the mixture was stirred at 25°C for 24 h; the reaction was monitored by use of HPLC equipped with a UV detector, the yield was calculated by HPLC analysis of a solution of known concn., the established yield is the radiochemical yield;
参考文献
Hylarides, Mark D.; Wilbur, D. Scott; adley, Stephen W.; Fritzberg, Alan R.
Journal of Organometallic Chemistry, 1989 , vol. 367, p. 259 - 266
N-chloro-succinimide in methanol; acetic acid to a soln. of B-compd.in MeOH was added one equivalent NaI in MeOH/AcOH and one equivalent NCS, the mixture was stirred for 15 min at 25°C; the reaction was monitored by use of HPLC equipped with a UV detector, the yield was calculated by HPLC analysis of a solution of known concn.;
参考文献
Hylarides, Mark D.; Wilbur, D. Scott; adley, Stephen W.; Fritzberg, Alan R.
Journal of Organometallic Chemistry, 1989 , vol. 367, p. 259 - 266
