4-溴-2-甲基-1-(甲基磺酰基)苯合成路线 （共 4 条）
反应条件
1: 4-bromo-2-methyl-benzene-sulfonyl chloride With sodium hydrogencarbonate; sodium sulfite in water
T=75°C; 1.16667 h;
2: monobromoacetic acid in water
T=105°C;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; HOFFMANN, Matthias; BISCHOFF, Daniel; DAHMANN, Georg; KLICIC, Jasna; SCHAENZLE, Gerhard; WOLLIN, Stefan Ludwig Michael; CONVERS-REIGNIER, Serge Gaston; EAST, Stephen Peter; MARLIN, Frederic Jacques; McCARTHY, Clive; SCOTT, John
Patent: US2013/29949 A1, 2013 ;
Location in patent: Paragraph 0181; 0182; 0183 ;
反应条件
copper(l) iodide in dimethyl sulfoxide
T=100 - 125°C; 3.33333 h; Microwave irradiation;
参考文献
Bristol-Myers Squibb Company
Patent: US2009/23702 A1, 2009 ;
Location in patent: Page/Page column 101 ;
US 20090023702 A1
反应条件
1: tetrachloromethane; N-bromo-succinimide
2: aqueous H2O2; acetic acid
View Scheme
参考文献
Groebel
Chemische Berichte, 1959 , vol. 92, p. 2887,2891
反应条件
dihydrogen peroxide; acetic acid
参考文献
Groebel
Chemische Berichte, 1959 , vol. 92, p. 2887,2891
