1-(4-硝基苯基)-3-羟基哌啶合成路线 （共 2 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=65°C; 6 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; EWING, William R.; ZHU, Yeheng; SUN, Chongqing; HUANG, Yanting; KARATHOLUVHU, Maheswaran Sivasamban; BOLTON, Scott A.; PASUNOORI, Laxman; MANDAL, Sunil Kumar; SHER, Philip M.
Patent: WO2013/12827 A1, 2013 ;
Location in patent: Paragraph 00199; 00229 ;
WO 2013/012827 A1
反应条件
N-ethyl-N,N-diisopropylamine in acetonitrile
18 h; Heating / reflux;
参考文献
PALAU PHARMA, S. A.
Patent: WO2008/90181 A1, 2008 ;
Location in patent: Page/Page column 65 ;
WO 2008/090181 A1
