3-(2,3-二氢-1H-吲哚-1-基)丙酸合成路线 (共 5 条)
反应条件
1: acetic acid; copper (I)-chloride
2: aqueous alkaline solution
View Scheme
参考文献
Astill; Boekelheide
Journal of Organic Chemistry, 1958 , vol. 23, p. 316
Full Text View citing articles Show Details
Rapoport; Tretter
Journal of Organic Chemistry, 1958 , vol. 23, p. 248,251
参考文献
Astill; Boekelheide
Journal of Organic Chemistry, 1958 , vol. 23, p. 316
Full Text View citing articles Show Details
Rapoport; Tretter
Journal of Organic Chemistry, 1958 , vol. 23, p. 248,251
反应条件
1: trifluoroacetic acid / dichloromethane / 40 °C
2: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane
3: potassium carbonate / N,N-dimethyl-formamide / 100 °C
4: methanol; water; lithium hydroxide hydrate
View Scheme
参考文献
Wu, Lingyun; Lu, Kai; Packiarajan, Mathivanan; Jubian, Vrej; Chandrasena, Gamini; Wolinsky, Toni C.; Walker, Mary W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 6 p. 2167 - 2171
反应条件
1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane
2: potassium carbonate / N,N-dimethyl-formamide / 100 °C
3: methanol; water; lithium hydroxide hydrate
View Scheme
参考文献
Wu, Lingyun; Lu, Kai; Packiarajan, Mathivanan; Jubian, Vrej; Chandrasena, Gamini; Wolinsky, Toni C.; Walker, Mary W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 6 p. 2167 - 2171
反应条件
methanol; water; lithium hydroxide hydrate
参考文献
Wu, Lingyun; Lu, Kai; Packiarajan, Mathivanan; Jubian, Vrej; Chandrasena, Gamini; Wolinsky, Toni C.; Walker, Mary W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 6 p. 2167 - 2171