1: 1a.) CuI, 1b.) HMPA / 1a.) THF, 0 deg C, 20 min, 1b.) -78 deg C, 15 min, 2.) -78 deg C 2: 100 percent / MCPBA / CH2Cl2 / 1 h / Ambient temperature 3: 91 percent / 5percent sodium amalgam / ethanol / 12 h / Heating 4: BF3*CH3COOH / CH2Cl2 / 2 h / Ambient temperature 5: MCPBA, KF / dimethylformamide / 40 h / Ambient temperature View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 1.) C₂H₅MgBr / 1.) ether, reflux, 1 h, 2.) ether, toluene, -20 deg C, 1 h<br />2: 95 percent / LAH / tetrahydrofuran / 0.5 h / -90 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 1.) C₂H₅MgBr / 1.) ether, reflux, 1 h, 2.) ether, toluene, -20 deg C, 1 h<br />2: 95 percent / LAH / tetrahydrofuran / 0.5 h / -90 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 86 percent / diethyl ether; toluene / 1 h / -20 &deg;C<br />2: 74 percent / diisobutylaluminum hydride / tetrahydrofuran / 0.17 h / -95 - -90 &deg;C<br /> <br /> &nbsp;