2-氯-5-甲氧基-4-嘧啶胺合成路线 (共 2 条)
反应条件
ammonium hydroxide in 1,4-dioxane T=100°C; 21 h; sealed tube;
参考文献
WO2011/59839 A1, ;
Page/Page column 91 ;
WO 2011/059839 A1
反应条件
1: ethyl acetate / 10 h / Reflux 2: hydroxylamine hydrochloride; sodium hydrogencarbonate / water; tert-butyl alcohol / 5 h / 20 °C 3: acetonitrile; methanol / 1.5 h / 20 °C View Scheme
参考文献
DOW AGROSCIENCES LLC
Patent: US2011/295003 A1, 2011 ;