1-甲基-1-吡啶-3-乙胺合成路线 (共 1 条)
反应条件
1: methyllithium With cerium(III) chloride in tetrahydrofuran; diethyl ether T=-78°C; 0.5 h; Inert atmosphere; 2: pyridine-3-carbonitrile in tetrahydrofuran; diethyl ether T=-78 - 20°C; 4 h; Inert atmosphere;
参考文献
Jaudzems, Kristaps; Tars, Kaspars; Maurops, Gundars; Ivdra, Natalija; Otikovs, Martins; Leitans, Janis; Kanepe-Lapsa, Iveta; Domraceva, Ilona; Mutule, Ilze; Trapencieris, Peteris; Blackman, Michael J.; Jirgensons, Aigars
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 4 p. 373 - 377