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| CAS号 : | 1916-07-0 |
精确质量 : | 226.08400 |
| 分子式 : | C11H14O5 |
logP : | 1.49900 |
| 分子量 : | 226.22600 |
PSA : | 53.99000 |
3,4,5-三甲氧基苯甲酸甲酯 | |
Methyl 3,4,5-trimethoxybenzoate | |
1916-07-0 | |
C11H14O5 | |
226.22600 | |
53.99000 | |
1.49900 | |
226.08400 |
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白色至灰白色结晶粉末
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1.494
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Stable under normal temperatures and pressures.
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274-275°C
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0.00538mmHg at 25°C
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Store in a cool, dry place. Store in a tightly closed container.
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82-84 °C(lit.)
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1.134 g/cm3
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274-275 °C(lit.)
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2918990090
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3
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S24/25
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DI0820000
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Xi
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HS: 2918990090 Other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives |
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品名, 成分含量, 用途 |
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2918990090. 其他含其他附加含氧基羧酸(包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
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2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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由没食子酸与硫酸二甲酯进行甲基化反应制得。将水、没食子酸、硫酸二甲酯加入反应锅,于15-35℃下滴加氢氧化钠溶液,在40℃左右搅拌半小时。再加入第二批硫酸二甲酯,在40℃左右滴加氢氧化钠溶液至pH为8-9。继续反应1h后,冷却,过滤,洗涤,干燥,得三甲氧基苯甲酸甲酯,收率90%以上。上述甲基化、酯化反应,也可采用四丁基溴化铵作相转移催化剂,在水和氯仿中进行。该品也可采用单宁酸为原料或由3,4,5-三甲氧基苯甲酸与甲醇酯化来制取 | |
用作医药中间体,是抗焦虑药曲美托嗪、肠胃药马来酸曲美布汀等的主要原料。 |