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| CAS号 : | 56-04-2 |
精确质量 : | 142.02000 |
| 分子式 : | C5H6N2OS |
logP : | 0.74090 |
| 分子量 : | 142.17900 |
PSA : | 80.74000 |
甲基硫脲嘧啶 | |
6-Methyl-2-thiouracil | |
56-04-2 | |
C5H6N2OS | |
142.17900 | |
80.74000 | |
0.74090 | |
142.02000 |
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1.638
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白色粉末
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160.8ºC
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342.3ºC at 760 mmHg
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~330 °C (dec.)(lit.)
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INSOLUBLE
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1.36 g/cm3
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Stability Incompatible with strong oxidizing agents, iodine, metals.
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Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
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GHS07, GHS08 | |
警告 | |
H302; H351 | |
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YR0875000
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29335995
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3
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S36/37-S45
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Xn
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R22; R40
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29335995. Other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. General tariff:6.5% |
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由乙酰乙酸乙酯与硫脲反应而得。将硫脲溶解于氢氧化钠溶液中,滴加乙酰乙酸乙酯,控制温度在37℃以下。反应2h后,加水和活性炭,在70-80℃脱色0.5h。过滤,滤液用盐酸酸化至pH4-5,冷却至室温,过滤,洗涤。滤饼用水重结晶,得成品。收率66%。生产中,也可先将乙酰乙酸乙酯和硫脲混合,再滴加氧化钠溶液;还可用无水碳酸钠代替氢氧化钠,收率大致相同。 | |
心血管药物潘生丁的中间体 |
