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| CAS号 : | 719-59-5 |
精确质量 : | 231.04500 |
| 分子式 : | C13H10ClNO |
logP : | 3.73440 |
| 分子量 : | 231.67800 |
PSA : | 43.09000 |
2-氨基-5-氯二苯甲酮 | |
2-Amino-5-chlorobenzophenone | |
719-59-5 | |
C13H10ClNO | |
231.67800 | |
43.09000 | |
3.73440 | |
231.04500 |
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1.636
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黄色结晶粉末
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库房通风低温干燥
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211 °C
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207 °C
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96-98 °C(lit.)
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1.33
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Stable. Incompatible with strong oxidizing agents.
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PC4933500
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3
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29223900
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S26-S36
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Xn
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R22
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29223900. Other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof. General tariff:6.5% |
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29223900. Other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof. General tariff:10.0% |
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(1)由对氯苯胺与苯甲酰氯反应制得。先将对氯苯加入搪玻璃反应锅中,在70℃以下,投入无水氯化锌,在搅拌下滴加苯甲酰氯,然后升温,在195-205℃保温2h后,用90-95℃的热水洗涤五次(水层及洗液回收苯甲酸与氯化锌)在100℃左右,将硫酸徐徐加入,在142℃保温40min。趁热将料液注入0-5℃水中,析出固体。在搅拌下,用液碱调节pH不高于1,在20-25℃时过滤。滤液回收对氯苯胺。滤饼混悬于水中,中和至pH=6,滤干,用水洗至中性,烘干得粗品。然后加6-7倍乙醇,6%活性炭,回流30min,过滤结晶,烘干而得精品。 | |
医药中间体。生产利眠安、安定等药物。 |
