1: 4-nitro-aniline; chloroacetyl chloride With triethylamine in tetrahydrofuran
T=20°C; 2.3 h; Cooling with ice;
2: piperidine in tetrahydrofuran
T=20°C; 14 h; Cooling with ice;
参考文献
Lombardo, Caterina Maria; Martinez, Iria Sanchez; Haider, Shozeb; Gabelica, Valerie; De Pauw, Edwin; Moses, John E.; Neidle, Stephen
Chemical Communications, 2010 , vol. 46, # 48 p. 9116 - 9118
Virsis, I. E.; Silaraya, D. A.; Grinberga, B. A.; Prikulis, A. A.; Gerbashevska, I. D.; Orenish, M. E.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 12 p. 849 - 853
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 12 p. 23 - 26
