反应条件
1: 1.) NaNO2, conc. HCl, 2.) Cu2O / 1.) acetone, water, 5 deg C, 30 min, 2.) acetone, water, 10 deg C 2: 2.) 2N HCl / 1.) sulfolane, 120 deg C, 5 h; 2.) sulfolane, 100 deg C, 15 h 3: 88.6 percent / hydrogen / 10percent Pd-C / methanol; ethyl acetate / 760 Torr / Ambient temperature View Scheme
参考文献
Sohda; Mizuno; Imamiya; Sugiyama; Fujita; Kawamatsu
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 10 p. 3580 - 3600
