1-(氯甲基)-4-硝基苯合成路线 (共 349 条)
反应条件
triethylamine in N,N-dimethyl-formamide T=0 - 5°C; 72 h;
参考文献
Zlotorzynska, Maria; Sammis, Glenn M.
Organic Letters, 2011 , vol. 13, # 23 p. 6264 - 6267
反应条件
triethylamine in tetrahydrofuran
参考文献
Sondheimer,E.; Semeraro,R.J.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1847 - 1849
反应条件
1: 71 percent / sodium ethoxide / ethanol / room temp. 4 h, reflux, 1 h 2: 96 percent / hydrogen / 5percent Pd/C / ethanol / Ambient temperature View Scheme
参考文献
Andreini; Biagi; Giorgi; Livi; Scartoni
Farmaco, 1989 , vol. 44, # 9 p. 831 - 841
反应条件
triethylamine in dichloromethane
反应条件
1,3-dimethylimidazolinium methanesulfonate T=90°C; 0.5 h;
参考文献
Brinchi; Germani; Savelli
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2027 - 2029
反应条件
triethylamine; sodium iodide in ethyl acetate 20 h; Heating;
参考文献
Wakselman; Cerutti; Chany
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 6 p. 519 - 526
参考文献
Grimaux
Zeitschrift fuer Chemie, 1867 , p. 562
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=20°C; Alkylation; 17 h;
参考文献
Tetrahedron Letters, , vol. 41, # 8 p. 1297 - 1301
反应条件
sodium ethanolate in ethanol room temp. 4 h, reflux, 1 h;
参考文献
Farmaco, , vol. 44, # 9 p. 831 - 841
反应条件
in methanol 2 h; Heating / reflux; Product distribution / selectivity;
参考文献
WO2006/137083 A1, ;
Abstract ;