2,6-二甲基-4-吡喃酮合成路线 （共 72 条）
反应条件
1: methanol; aqueous sodium iodide
2: ethanol
View Scheme
参考文献
Anker; Cook
Journal of the Chemical Society, 1946 , p. 117,119
反应条件
1: With potassium tert-butylate in tert-butyl alcohol
T=150°C; 0.5 h; Microwave irradiation;
2: With hydrogenchloride in water; tert-butyl alcohol
1 h; Reflux;
参考文献
Marshall, Laura J.; Cable, Karl M.; Botting, Nigel P.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 457 - 459
反应条件
1: dichloromethane
2: ammonium carbonate
View Scheme
参考文献
Meerwein et al.
Journal fuer Praktische Chemie (Leipzig), 1937 , vol. <2>147, p. 268
Journal fuer Praktische Chemie (Leipzig), 1940 , vol. <2>154, p. 111,130,131
参考文献
Campbell et al.
Journal of Organic Chemistry, 1950 , vol. 15, p. 337,338
反应条件
in water
Ambient temperature;
参考文献
Gold, Victor; Mah, Talat
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 812 - 816
反应条件
1: 69.8 percent / acetic anhydride / 8 h / Heating
2: 63 percent / potassium carbonate / acetonitrile / 72 h / Heating
3: 97.7 percent / copper acetate / dioxane / 1 h / Heating
View Scheme
参考文献
Clairc; Le Baut; Ploquin; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 529 - 532
反应条件
1: 69.8 percent / acetic anhydride / 8 h / Heating
2: 10 percent / potassium carbonate / acetonitrile / 72 h / Heating
View Scheme
参考文献
Clairc; Le Baut; Ploquin; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 529 - 532
反应条件
1: palladium; nickel catalyst; ethanol / Hydrogenation.und Behandlung mit Chrom(VI)-oxid und wss. Schwefelsaeure
View Scheme
参考文献
de Vrieze
Recueil des Travaux Chimiques des Pays-Bas, 1947 , vol. 66, p. 486,488
反应条件
Behandeln des Reaktionsprodukts mit Ueberchlorsaeure;
参考文献
Baeyer; Piccard
Justus Liebigs Annalen der Chemie, 1911 , vol. 384, p. 220
Justus Liebigs Annalen der Chemie, 1915 , vol. 407, p. 339
反应条件
sodium ethanolate in ethanol
Heating;
参考文献
Takagi; Bastian; Hubert Habart; Royer
European Journal of Medicinal Chemistry, 1974 , vol. 9, # 3 p. 255 - 258
