(2R,3S)-N-苄氧羰基-2,3-二苯基吗啉-6-酮合成路线 （共 8 条）
反应条件
toluene-4-sulfonic acid; calcium chloride in benzene 8 h; Heating;
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: aq. NaHCO3 / CH2Cl2 / 1 h / 0 °C 3: p-TsOH*H2O / toluene View Scheme
参考文献
Synlett, , # 4 art. no. Y04304ST, p. 693 - 696
反应条件
1: aq. NaHCO3 / CH2Cl2 / 1 h / 0 °C 2: p-TsOH*H2O / toluene View Scheme
参考文献
Synlett, , # 4 art. no. Y04304ST, p. 693 - 696
反应条件
2: Et3N / tetrahydrofuran / 25 °C 3: NaHCO3 / CH2Cl2; H2O 4: p-TsOH / benzene / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 108, # 5 p. 1103 - 1104
反应条件
sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine 1.) THF, 2.) CH2Cl2, 3.) benzene, reflux; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 36, # 6 p. 825 - 828
反应条件
N-bromosuccinmide in tetrachloromethane 0.75 h; Heating;
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
N-bromosuccinmide 1) CCl4, 2) THF; Yield given. Multistep reaction;
参考文献
Williams; Fegley
Tetrahedron Letters, 1992 , vol. 33, # 45 p. 6755 - 6758
反应条件
1: NBS / CCl4 / 0.58 h / Heating 2: 1.) ZnCl2, 2.) H2 / 2.) PdCl2 / 1.) THF, 25 deg C, 2.) EtOH, 25 deg C, p= 20 psi View Scheme
参考文献
Sinclair, Peter J.; Zhai, Dongguan; Reibenspies, Joseph; Williams, Robert M.
Journal of the American Chemical Society, 1986 , vol. 108, # 5 p. 1103 - 1104
