5-(乙酰氧甲基)-4-乙基-3-甲基-1H-吡咯-2-羧酸乙酯合成路线 （共 9 条）
反应条件
acetic anhydride in acetic acid T=20°C; Acetoxylation; 3 h;
参考文献
Lash, Timothy D.
Tetrahedron, 1998 , vol. 54, # 3-4 p. 359 - 374
反应条件
acetic anhydride; acetic acid T=20°C;
参考文献
Lash, Timothy D.; Chen, Shaohua
Tetrahedron, 2005 , vol. 61, # 49 p. 11577 - 11600
反应条件
lead(IV) acetate 2 h;
参考文献
Berezin, M. B.; Semeikin, A. S.; V'yugin, A. I.
Russian Journal of Physical Chemistry, 1996 , vol. 70, # 8 p. 1265 - 1268
Zhurnal Fizicheskoi Khimii, 1996 , vol. 70, # 8 p. 1634 - 1636
参考文献
Siedel; Winkler
Justus Liebigs Annalen der Chemie, 1943 , vol. 554, p. 162,185
反应条件
hydrogenchloride in methanol Condensation; 3 h; Heating;
参考文献
Lash, Timothy D.
Tetrahedron, 1998 , vol. 54, # 3-4 p. 359 - 374
反应条件
1: 81 percent / Montmorillonite clay K-10 / CH2Cl2 / 20 °C
2: NaOH / ethane-1,2-diol / 1 h / Heating
View Scheme
参考文献
Lash, Timothy D.; Chen, Shaohua
Tetrahedron, 2005 , vol. 61, # 49 p. 11577 - 11600
反应条件
1: 53 percent / p-toluenesulfonic acid / CH2Cl2 / 48 h / 40 °C
2: 92 percent / NaOH / ethane-1,2-diol / 1.5 h / Heating
View Scheme
参考文献
Juillard, Sandrine; Simonneaux, Gerard
Synlett, 2006 , # 17 p. 2818 - 2820
反应条件
1: 81 percent / HCl / methanol / 3 h / Heating
2: NaOH / ethane-1,2-diol / 1 h / Heating
View Scheme
参考文献
Lash, Timothy D.
Tetrahedron, 1998 , vol. 54, # 3-4 p. 359 - 374
反应条件
1.1: 81 percent / HCl / methanol / 3 h / Heating
2.1: NaOH / ethane-1,2-diol / 1 h / Heating
3.1: 162 mg / HBr; AcOH / methanol / 0.5 h / 20 °C
4.1: CuCl2 / dimethylformamide / 4 h / 20 °C
4.2: 31 percent / H2SO4; CF3CO2H / 0.75 h / 20 °C
View Scheme
参考文献
Lash, Timothy D.; Chen, Shaohua
Tetrahedron, 2005 , vol. 61, # 49 p. 11577 - 11600
