(6-溴萘-2-基氧基)-叔丁基二甲基硅烷合成路线 （共 5 条）
反应条件
1H-imidazole in dichloromethane T=20°C; 2 h;
参考文献
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Patent: WO2008/124812 A1, 2008 ;
Location in patent: Page/Page column 48-49 ;
反应条件
in N,N-dimethylformamide (DMF)
参考文献
PARION SCIENCES, Inc.
Patent: US2009/214444 A1, 2009 ;
US 20090214444 A1
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide
参考文献
Wyeth
Patent: US2003/181519 A1, 2003 ;
反应条件
in diethyl ether; water; N,N-dimethyl-formamide
参考文献
Agejas-Chicharro, Javier; Belen Bueno Melendo, Ana; Camp, Nicholas Paul; Gilmore, Jeremy; Jimenez-Aguado, Alma Maria; Lamas-Peteira, Carlos; Marcos-Llorente, Alicia; Mazanetz, Michael Philip; Montero Salgado, Carlos; Timms, Graham Henry; Williams, Andrew Caerwyn
Patent: US2004/122001 A1, 2004 ;
US 20040122001 A1
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 3: With hydrogenchloride in tetrahydrofuran; hexane T=0°C; 0.166667 h;
参考文献
Mewshaw, Richard E.; Edsall Jr., Richard J.; Yang, Cuijian; Manas, Eric S.; Xu, Zhang B.; Henderson, Ruth A.; Keith Jr., James C.; Harris, Heather A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 12 p. 3953 - 3979
