2,2-二甲氧基丙酸甲酯合成路线 （共 25 条）
反应条件
hydroquinone in quinoline
参考文献
Chevron Research Company
Patent: US4304928 A1, 1981 ;
反应条件
sodium methylate in 1,4-dioxane
参考文献
DSM Chemie Linz GmbH
Patent: US5898076 A1, 1999 ;
反应条件
toluene-4-sulfonic acid
1.) 120 deg C, 3 h, benzene; 2.) 160 -180 deg C; Yield given. Multistep reaction;
参考文献
Berryhill; Price; Rosenblum
Journal of Organic Chemistry, 1983 , vol. 48, # 2 p. 158 - 162
反应条件
n-butyllithium; diisopropylamine
1.) THF, hexane, -78 deg C, 20 min, 2.) 20 min; Yield given. Multistep reaction;
参考文献
Cameron, Andrew G.; Hewson, Alan T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2979 - 2983
反应条件
lithium aluminium tetrahydride in diethyl ether
T=20°C; Reduction; 1 h;
参考文献
Aso, Mariko; Kondo, Mitsumasa; Suemune, Hiroshi; Hecht, Sidney M.
Journal of the American Chemical Society, 1999 , vol. 121, # 39 p. 9023 - 9033
