1,1’-亚甲基双(4-氯苯)合成路线 （共 54 条）
反应条件
chromic acid; acetic acid
参考文献
Barbiero; Kim; Hay
Tetrahedron Letters, 1994 , vol. 35, # 32 p. 5833 - 5836
参考文献
Stephen; Short; Gladding
Journal of the Chemical Society, 1920 , vol. 117, p. 525
反应条件
gallium trifluoromethanesulfonate; dimethylmono-chlorosilane in dichloromethane
T=20°C; 0.5 h;
参考文献
Surya Prakash; Do, Clement; Mathew, Thomas; Olah, George A.
Catalysis Letters, 2011 , vol. 141, # 4 p. 507 - 511
反应条件
iodine; hypophosphorous acid in acetic acid
T=60°C; 24 h;
参考文献
Gordon, Paul E.; Fry, Albert J.
Tetrahedron Letters, 2001 , vol. 42, # 5 p. 831 - 833
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in water; N,N-dimethyl-formamide
T=153°C; 12 h;
参考文献
Wang, Xing; Liu, Lian-Hua; Shi, Jin-Hua; Peng, Ji; Tu, Hai-Yang; Zhang, Ai-Dong
European Journal of Organic Chemistry, 2013 , # 30 p. 6870 - 6877
反应条件
potassium hydroxide in diethylene glycol
T=150 - 155°C; 5 h;
参考文献
Kuz'mina, N. A.; Vakhtangishvili, L. V.; Rusanov, A. L.; Fidler, S. Kh.; Chukovskaya, E. Ts.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 6 p. 1311 - 1313
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 6 p. 1443 - 1446
反应条件
potassium hydroxide in ethylene glycol
6 h; Heating;
参考文献
Novakovski, E.
Journal of Organic Chemistry USSR (English Translation), 1981 , p. 1319 - 1322
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 7 p. 1482 - 1486
反应条件
trifluorormethanesulfonic acid in chloroform
T=60°C; 5 h;
参考文献
Gautret, Philippe; El-Ghammarti, Samira; Legrand, Anne; Couturier, Daniel; Rigo, Benoit
Synthetic Communications, 1996 , vol. 26, # 4 p. 707 - 713
反应条件
1: With Pd0(tris(tert-butyl)phosphine)2; potassium hydroxide in 1,4-dioxane; water
T=20°C; Suzuki-Miyaura Coupling; 12 h; Inert atmosphere;
2: With potassium hydroxide in 1,4-dioxane; water
T=60°C; Suzuki-Miyaura Coupling; 2 h; Inert atmosphere;
参考文献
Endo, Kohei; Ishioka, Takafumi; Ohkubo, Takahiro; Shibata, Takanori
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7223 - 7231
反应条件
catalyst: K-L zeolite in dichloromethane
Kinetics; byproducts: 2-chlorodiphenylmethane, 4-chlorodiphenylmethane, HCl; at 315 K for 1 h; catalyst K-L zeolite; yields: 2-chlorodiphenylmethane 10.7 wt.percent, 4-chlorodiphenylmethane 1.4 wt.percent; not isolated; detd. by gas-chromy.;
参考文献
Kale; Singh
Journal of Molecular Catalysis A: Chemical, 2002 , vol. 184, # 1-2 p. 399 - 411
