1-(吡啶-3-基)-1 H-吡唑-4-甲酸合成路线 (共 2 条)
反应条件
1: With water; sodium hydroxide in 1,4-dioxane 24 h; Reflux; 2: With hydrogenchloride in water T=0°C; pH=3;
参考文献
Bayer CropScience AG
Patent: US2011/118290 A1, 2011 ;
Location in patent: Page/Page column 14 ;
反应条件
1.1: potassium carbonate / copper(l) iodide; trans-N,N'-dimethylcyclohexane-1,2-diamine / 24 h / 110 °C / Inert atmosphere 2.1: sodium hydroxide; water / 1,4-dioxane / 24 h / Reflux 2.2: 0 °C / pH 3 View Scheme
参考文献
Bayer CropScience AG
Patent: US2012/95023 A1, 2012 ;