5,6,7,8-四氢-3-喹啉腈合成路线 （共 6 条）
反应条件
1: With sodium acetate; zinc in acetic acid T=60°C; 2 h; 2: With water in acetic acid T=60°C; 5 h;
参考文献
F. HOFFMANN-LA ROCHE AG; SIENA BIOTECH S.P.A; HILPERT, Hans; NARQUIZIAN, Robert; PINARD, Emmanuel; POLARA, Alessandra; ROGERS-EVANS, Mark; WOLTERING, Thomas; WOSTL, Wolfgang
Patent: WO2012/156284 A1, 2012 ;
Location in patent: Page/Page column 133 ;
反应条件
acetic acid; zinc in ethanol 0.75 h; Heating;
参考文献
Paine, John B.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 351 - 355
反应条件
1: piperidine acetate / H2O / 4 h / Heating 2: 48 percent / PBr3 / Heating 3: 59 percent / Zn-dust, acetic acid / ethanol / 0.75 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, p. 351 - 355
反应条件
1: NaOCH3 / ethanol; diethyl ether / standing overnight 2: piperidine acetate / H2O / 4 h / Heating 3: 48 percent / PBr3 / Heating 4: 59 percent / Zn-dust, acetic acid / ethanol / 0.75 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, p. 351 - 355
反应条件
1: 48 percent / PBr3 / Heating 2: 59 percent / Zn-dust, acetic acid / ethanol / 0.75 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, p. 351 - 355
反应条件
hydrogenchloride; water 8 h; Heating;
参考文献
Paine, John B.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 351 - 355
