1: benzyl-methyl-amine With ethyl-α,α,α-trifluoroacetate T=0 - 22°C; 0.5 h; 2: (S)-2-[N-(t-butoxycarbonyl)amino]-3-(naphth-2-yl)-propionic acid With 4-methyl-morpholine in ethyl acetate T=-15°C; 0.25 h; 3: isobutyl chloroformate in ethyl acetate T=-15°C; 1 h;
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Prashad, Mahavir; Prasad, Kapa; Repic, Oljan; Blacklock, Thomas J.; Prikoszovich, Walter
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1: benzyl-methyl-amine With REM resin T=20°C; 3 h; 2: benzyl bromide in N,N-dimethyl-formamide 18 h; 3: With N-ethyl-N,N-diisopropylamine in dichloromethane
参考文献
Morphy; Rankovic, Zoran; York, Mark
Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7509 - 7511
3 platinum on carbon; hydrogen in toluene T=105°C; P=4500.45 Torr; Flow reactor;
参考文献
Sharma, Sumeet K.; Lynch, James; Sobolewska, Anna M.; Plucinski, Pawel; Watson, Robert J.; Williams, Jonathan M. J.
Catalysis Science and Technology, 2013 , vol. 3, # 1 p. 85 - 88
