1: azidobenzoic acid in toluene
T=100°C; Curtius rearrangement; 2 h;
2: in toluene
T=100°C;
3: benzyl-methyl-amine With triethylamine in acetonitrile
T=70°C; Further stages.;
1: With 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
P=760.051 Torr; 0.75 h;
2: With tributylphosphine; di-tert-butylazodicarboxylate in acetonitrile
Mitsunobu reaction; Inert atmosphere;
参考文献
Peterson, Scott L.; Stucka, Sabrina M.; Dinsmore, Christopher J.
Organic Letters, 2010 , vol. 12, # 6 p. 1340 - 1343