1: phenylacetic acid With sodium hydroxide in DMF (N,N-dimethyl-formamide); water T=4°C; 1 h; 2: 2-bromo-l-(4-(methylsulfonyl)-phenyl)-ethanone With diisopropylamine T=45°C; 3.5 h;
参考文献
MERCK and CO., INC.
Patent: EP912537 B1, 2004 ;
Location in patent: Page 13 ;
