5,5,8,8-四甲基-5,6,7,8-四氢-2-萘羧酸合成路线 （共 10 条）
反应条件
1: With potassium permanganate; sodium hydroxide in pyridine; water T=95°C; 16 h; 2: With hydrogenchloride in pyridine; water T=1°C; pH=1;
参考文献
Gurkan, A. Selen; Karabay, Arzu Z.; Buyukbingol, Zeliha; Buyukbingol, Erdem
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 468 - 479
反应条件
1: With sodium hydroxide in ethanol; dichloromethane; water T=20°C; 20 h; 2: With hydrogenchloride in ethanol; dichloromethane; water
参考文献
EP1357104 A1, ;
Page/Page column 13-14 ;
反应条件
ammonium cerium(IV) nitrate; acetic acid T=100°C; 0.25 h;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 7 p. 1504 - 1517
反应条件
sodium hydroxide in 1,4-dioxane
反应条件
1: AlCl3 2: aq. NaOH, KMnO4 / pyridine View Scheme
参考文献
Journal of Organic Chemistry, , vol. 25, p. 708 - 711
反应条件
1: AlCl3 2: aq. NaOH, KMnO4 / pyridine View Scheme
参考文献
Journal of Organic Chemistry, , vol. 25, p. 708 - 711
反应条件
1: hydrogenchloride / ethanol 2: AlCl3, aluminium chloride 3: potassium permanganate / Alkaline conditions View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 2 p. 468 - 479
反应条件
sodium azide; sulfuric acid in chloroform
参考文献
Myhre,P.C.; Schubert,W.M.
Journal of Organic Chemistry, 1960 , vol. 25, p. 708 - 711
反应条件
1: NaN3, aq. H2SO4 / CHCl3 2: aq. HCl, NaNO2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 25, p. 708 - 711
反应条件
1: 1.) SOCl2, 2.) 4-(dimethylamino)pyridine / 1.) 0 deg C, 30 min, 2.) pyridine, 60 deg C, 2 h 2: 77.2 percent / aq. NaOH / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
