2-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇合成路线

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

参考文献

Devasthale, Pratik V.; Chen, Sean; Jeon, Yoon; Qu, Fucheng; Shao, Chunning; Wang, Wei; Zhang, Hao; Cap, Michael; Farrelly, Dennis; Golla, Rajasree; Grover, Gary; Harrity, Thomas; Ma, Zhengping; Moore, Lisa; Ren, Jimmy; Seethala, Ramakrishna; Cheng, Lin; Sleph, Paul; Sun, Wei; Tieman, Aaron; Wetterau, John R.; Doweyko, Arthur; Chandrasena, Gamini; Chang, Shu Y.; Humphreys, W. Griffith; Sasseville, Vito G.; Biller, Scott A.; Ryono, Denis E.; Selan, Fred; Hariharan, Narayanan; Cheng, Peter T. W.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 2248 - 2250

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

196808-45-4法格立他扎

参考文献

Collins, Jon L.; Blanchard, Steven G.; Boswell, G. Evan; Charifson, Paul S.; Cobb, Jeff E.; Henke, Brad R.; Hull-Ryde, Emily A.; Kazmierski, Wieslaw M.; Lake, Debra H.; Leesnitzer, Lisa M.; Lehmann, Juergen; Lenhard, James M.; Orband-Miller, Lisa A.; Gray-Nunez, Yolanda; Parks, Derek J.; Plunkett, Kelli D.; Tong, Wei-Qin
Journal of Medicinal Chemistry, 1998 , vol. 41, # 25 p. 5037 - 5054

123-08-0对羟基苯甲醛+

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

103788-59-64-[2-(5-甲基-2-苯基-1,3-恶唑-4-基)乙氧基]苯甲醛

参考文献

PFIZER INC.
Patent: WO2004/92145 A1, 2004 ;
Location in patent: Page 95 ;
WO 2004/092145 A1

123-08-0对羟基苯甲醛+

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇+

1972-28-7偶氮二甲酸二乙酯

103788-59-64-[2-(5-甲基-2-苯基-1,3-恶唑-4-基)乙氧基]苯甲醛

参考文献

Pfizer Inc
Patent: US2005/187266 A1, 2005 ;

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

103788-59-64-[2-(5-甲基-2-苯基-1,3-恶唑-4-基)乙氧基]苯甲醛

参考文献

Sohda; Mizuno; Momose; Ikeda; Fujita; Meguro
Journal of Medicinal Chemistry, 1992 , vol. 35, # 14 p. 2617 - 2626

459-57-4对氟苯甲醛+

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

103788-59-64-[2-(5-甲基-2-苯基-1,3-恶唑-4-基)乙氧基]苯甲醛

参考文献

Imoto, Hiroshi; Sugiyama, Yasuo; Kimura, Hiroyuki; Momose, Yu
Chemical and Pharmaceutical Bulletin, 2003 , vol. 51, # 2 p. 138 - 151

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

331746-72-6

参考文献

Humphries, Paul S.; Bailey, Simon; Almaden, Jonathon V.; Barnum, Sandra J.; Carlson, Thomas J.; Christie, Lance C.; Do, Quyen-Quyen T.; Fraser, James D.; Hess, Mary; Kellum, Jack; Kim, Young H.; McClellan, Guy A.; Ogilvie, Kathleen M.; Simmons, Brett H.; Skalitzky, Donald; Sun, Shaoxian; Wilhite, David; Zehnder, Luke R.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6120 - 6123

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

331746-65-7N-[[4-[2-(5-甲基-2-苯基-4-恶唑基)乙氧基]苯基]甲基]甘氨酸甲酯

参考文献

Devasthale, Pratik V.; Chen, Sean; Jeon, Yoon; Qu, Fucheng; Shao, Chunning; Wang, Wei; Zhang, Hao; Cap, Michael; Farrelly, Dennis; Golla, Rajasree; Grover, Gary; Harrity, Thomas; Ma, Zhengping; Moore, Lisa; Ren, Jimmy; Seethala, Ramakrishna; Cheng, Lin; Sleph, Paul; Sun, Wei; Tieman, Aaron; Wetterau, John R.; Doweyko, Arthur; Chandrasena, Gamini; Chang, Shu Y.; Humphreys, W. Griffith; Sasseville, Vito G.; Biller, Scott A.; Ryono, Denis E.; Selan, Fred; Hariharan, Narayanan; Cheng, Peter T. W.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 2248 - 2250

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

784149-40-2

参考文献

Humphries, Paul S.; Bailey, Simon; Almaden, Jonathon V.; Barnum, Sandra J.; Carlson, Thomas J.; Christie, Lance C.; Do, Quyen-Quyen T.; Fraser, James D.; Hess, Mary; Kellum, Jack; Kim, Young H.; McClellan, Guy A.; Ogilvie, Kathleen M.; Simmons, Brett H.; Skalitzky, Donald; Sun, Shaoxian; Wilhite, David; Zehnder, Luke R.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6120 - 6123

103788-65-42-(5-甲基-2-苯基-1,3-恶唑-4-基)-1-乙醇

669077-49-03-{4-[2-(5-甲基-2-苯基-1,3-恶唑-4-基)乙氧基]-1H-吲唑-1-基}丙酸

参考文献

Saenz, James; Mitchell, Mark; Bahmanyar, Sami; Stankovic, Nebojsa; Perry, Michael; Craig-Woods, Bridgette; Kline, Billie; Yu, Shu; Albizati, Kim
Organic Process Research and Development, 2007 , vol. 11, # 1 p. 30 - 38