8-溴-1,3,7-三甲基嘌呤-2,6-二酮合成路线 （共 18 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C; 6 h;
参考文献
PROTEOTECH INC; ESPOSITO, Luke; HANSON, Kelsey; YADON, Marisa, C.; LAKE, Thomas; KUMAR, Anil; SNOW, Alan, D.; CUMMINGS, Joel
Patent: WO2013/62762 A1, 2013 ;
Location in patent: Page/Page column 39; 40 ;
反应条件
N-bromosuccinmide in dichloromethane; water 120 h;
参考文献
Soltani Rad, Mohammad Navid; Behrouz, Somayeh; Nekoei, Abdo-Reza
Synlett, 2012 , vol. 23, # 8 p. 1191 - 1198
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 6 h;
参考文献
Vollmann, Karl; Mueller, Christa E.
Heterocycles, 2002 , vol. 57, # 5 p. 871 - 879
反应条件
complex (KBr*BrCN)n in water T=60°C; 2 h;
参考文献
Skulski, Lech; Wroczynski, Piotr
Polish Journal of Chemistry, 1982 , vol. 56, # 7/8/9 p. 975 - 982
反应条件
complex (KBr*BrCN)n in water T=60°C; 2 h;
参考文献
Skulski, Lech; Wroczynski, Piotr
Polish Journal of Chemistry, 1982 , vol. 56, # 7/8/9 p. 975 - 982
反应条件
potassium hydroxide T=80°C;
参考文献
Fischer,E.; Reese
Justus Liebigs Annalen der Chemie, 1883 , vol. 221, p. 344
反应条件
water; hydrogen bromide
参考文献
Cacace; Masironi
Annali di Chimica (Rome, Italy), 1957 , vol. 47, p. 362,364
参考文献
Biltz; Beck
Journal fuer Praktische Chemie (Leipzig), 1928 , vol. <2>118, p. 161
反应条件
Zersetzen des Reaktionsprodukts mit Eis und Salzsaeure;
参考文献
Chemische Berichte, , vol. 40, p. 1747
反应条件
hydroxylamine hydrochloride; 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide Microwave irradiation;
参考文献
Soltani Rad, Mohammad Navid; Behrouz, Somayeh; Nekoei, Abdo-Reza
Synlett, 2012 , vol. 23, # 8 p. 1191 - 1198
