5-乙基-2-甲基-吡啶合成路线 （共 107 条）
反应条件
1: With 3-chloro-benzenecarboperoxoic acid in dichloromethane T=0 - 20°C; 2.5 h; 2: With trifluoroacetic anhydride in dichloromethane 3.5 h; Heating / reflux; 3: With sodium methylate; manganese(IV) oxide more than 3 stages;
参考文献
Leitis, L. Ya.; Skolmeistere, R. A.; Golender, L. O.; Yansone, D. P.; Meksh, P. A.; Shimanskaya, M. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 1 p. 63 - 66
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 1 p. 75 - 79
反应条件
1: nitric acid; sulfuric acid / 150 °C 2: hydrazine hydrate / ethanol / 2 h / |Reflux View Scheme
参考文献
Shyma; Kalluraya, Balakrishna; Peethambar; Telkar, Sandeep; Arulmoli
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 394 - 404
反应条件
selenium(IV) oxide; sulfuric acid T=300 - 350°C;
参考文献
Abbott Labor.
Patent: US2905688 , 1954 ;
参考文献
Jordan
Industrial and Engineering Chemistry, 1952 , vol. 44, p. 332
反应条件
1: With sulfuric acid; acetic anhydride; acetic acid 2: With chromium(VI) oxide T=10 - 20°C; 3: With sodium carbonate in water
参考文献
WO2010/67085 A2, ;
Page/Page column 58 ;
反应条件
1: 180 °C 2: palladium/charcoal; ethanol / Hydrogenation View Scheme
参考文献
Graf; Langer
Journal fuer Praktische Chemie (Leipzig), 1938 , vol. <2> 150, p. 153,155
参考文献
Rosania, Gustavo R.; Lee, Jae Wook; Ding, Liang; Yoon, Hai-Shin; Chang, Young-Tae
Journal of the American Chemical Society, 2003 , vol. 125, # 5 p. 1130 - 1131
反应条件
hydrogen; aluminum oxide; nickel T=330°C; P=750.06 Torr; Product distribution;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 18, # 3 p. 280 - 283
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 18, # 3 p. 371 - 374
反应条件
potassium permanganate in water T=90°C; 0.433333 h;
参考文献
Pharmaceutical Chemistry Journal, , vol. 26, # 11/12 p. 894 - 896
Khimiko-Farmatsevticheskii Zhurnal, , vol. 26, # 11-12 p. 81 - 83
反应条件
selenium(IV) oxide T=115°C;
参考文献
Jerchel et al.
Justus Liebigs Annalen der Chemie, 1958 , vol. 613, p. 153,155, 162
