甲基6-(二甲氧基磷酰)-5-氧代己酸酯合成路线 （共 8 条）
反应条件
trifluoroacetic acid 10 h; Heating;
参考文献
Wenkert; Guo; Lavilla; Porter; Ramachandran; Sheu
Journal of Organic Chemistry, 1990 , vol. 55, # 25 p. 6203 - 6214
反应条件
1: 78 percent / HCl (g) 2: 35 percent / NaI View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 28 p. 4849 - 4852
参考文献
Adiyaman, Mustafa; Lawson, John A.; Hwang, Seong-Woo; Khanapure, Subhash P.; FitzGerald, Garret A.; Rokach, Joshua
Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4849 - 4852
反应条件
1: sodium iodide / acetonitrile / 24 h 2: acetonitrile / 12 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 9 p. 3725 - 3732
反应条件
1: 1) n-butyllithium / 1) hexane, THF, -78 deg C, 2a) THF, -78 deg C, 2 h, 2b) warm to RT 2: 95 percent / trifluororacetic acid / 10 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 25 p. 6203 - 6214
反应条件
in acetonitrile T=20°C; 12 h;
参考文献
Gore, Vivek; Patel, Pranav; Chang, Chih-Tsung; Sivendran, Sashikala; Kang, Namin; Ouedraogo, Yannick P.; Gravel, Sylvie; Powell, William S.; Rokach, Joshua
Journal of Medicinal Chemistry, 2013 , vol. 56, # 9 p. 3725 - 3732
反应条件
n-butyllithium 1.) hexane, THF, -78 deg C, -78 deg C, 2.) -78 deg C, 3.5 h.; Yield given. Multistep reaction;
参考文献
Russian Journal of Organic Chemistry, , vol. 33, # 1 p. 47 - 54
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 59, # 18 p. 5453 - 5457
