2-氨基-5-三氟甲基-1,3,4-噻二唑合成路线 （共 33 条）
反应条件
T=-5 - 40°C; 3 h; Inert atmosphere;
参考文献
Alegaon, Shankar G.; Alagawadi, Kallanagouda R.
Medicinal Chemistry Research, 2012 , vol. 21, # 6 p. 816 - 824
反应条件
sulfuric acid T=99.85°C; 7 h;
参考文献
Boechat, Nubia; Ferreira, Sabrina B.; Glidewell, Christopher; Low, John N.; Skakle, Janet M.S.; Wardell, Solange M.S.V.
Acta Crystallographica Section C: Crystal Structure Communications, 2006 , vol. 62, # 1 p. o42-o44
反应条件
tert.-butylhydroperoxide; TPGS-750-M in water T=-5 - 23°C; 38 h; Green chemistry;
参考文献
Fennewald, James C.; Lipshutz, Bruce H.
Green Chemistry, 2014 , vol. 16, # 3 p. 1097 - 1100
反应条件
biscyclopentadienyliron(II); dihydrogen peroxide in water; dimethyl sulfoxide
参考文献
Kino, Tatsuhito; Nagase, Yu; Ohtsuka, Yuhki; Yamamoto, Kyoko; Uraguchi, Daisuke; Tokuhisa, Kenji; Yamakawa, Tetsu
Journal of Fluorine Chemistry, 2010 , vol. 131, # 1 p. 98 - 105
反应条件
sulfuric acid reacting thiosemicarbazide with (CF3C(O)Cl, followed by treating with H2SO4;
参考文献
GB1333495 , ;
C.A., , vol. 80, p. 37115
反应条件
after diazotization of 2-amino-5-trifluoromethyl-1,3,4-thiadiazole in modified Sandmeyer reaction;
参考文献
Gmelin Handbook: F: PerFHalOrg.SVol.2, 6.2.1.5.2, page 41 - 61
参考文献
Gmelin Handbook: F: PerFHalOrg.SVol.2, 6.2.1.5.2, page 41 - 61
参考文献
Gmelin Handbook: F: PerFHalOrg.SVol.2, 6.2.1.5.2, page 41 - 61
反应条件
acid chloride; pyridine or anhydride
参考文献
Lalezari, I.; Sharghi, N.
J. Heterocyclic Chem., 1966 , vol. 3, p. 336 - 337
Full Text Show Details
Gmelin Handbook: F: PerFHalOrg.1, 1.1.5.4, page 89 - 94
Full Text Show Details
Farbenfabriken Bayer A. G.
Patent: ZA6904818 , 1969 ;
C.A., 1970 , vol. 73, p. 45515
Full Text Show Details
Farbenfabriken Bayer A. G.
Patent: DE1795037 , 1969 ;
反应条件
in N,N-dimethyl-formamide Ambient temperature;
参考文献
Gyoerfi, Z.; Csavassy, Gy.
Acta Chimica Academiae Scientiarum Hungaricae, 1980 , vol. 103, # 1 p. 87 - 94
