1,5-二甲基-1H-咪唑合成路线 （共 23 条）
参考文献
Journal of the Chemical Society, , vol. 83, p. 440,454
Journal of the Chemical Society, , vol. 87, p. 797
反应条件
beim Durchleiten durch ein auf Rotglut erhitztes Glasrohr;
参考文献
Jowett; Potter
Journal of the Chemical Society, 1903 , vol. 83, p. 469
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Pyman
Journal of the Chemical Society, 1910 , vol. 97, p. 1820
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Windaus
Chemische Berichte, 1906 , vol. 39, p. 3889
反应条件
bromocyane in acetonitrile Ambient temperature;
参考文献
McCallum, Peter B.W.; Weavers, Rex T.; Grimmett, M. Ross; Blackman, Allan G.
Australian Journal of Chemistry, 1999 , vol. 52, # 3 p. 159 - 165
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; diisobutylaluminium hydride in 1,4-dioxane
T=100°C; 2.5 h;
参考文献
Gibson, Christoph; Schnatbaum, Karsten; Pfeifer, Jochen R.; Locardi, Elsa; Paschke, Matthias; Reimer, Ulf; Richter, Uwe; Scharn, Dirk; Faussner, Alexander; Tradler, Thomas
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4370 - 4379
参考文献
Pyman
Journal of the Chemical Society, 1922 , vol. 121, p. 2624
反应条件
1: 4(5)-methyl-1H-imidazole With triethylamine; benzenesulfonyl chloride in acetonitrile
8 h; Inert atmosphere;
2: methyl trifluoromethanesulfonate in acetonitrile
24 h; Inert atmosphere;
3: With N-methyl-N-butylamine in acetonitrile
T=80°C; Inert atmosphereHeating; regioselective reaction;
参考文献
Van Den Berge, Emilie; Robiette, Raphael
Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 12220 - 12223
反应条件
in benzene
T=140°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kashima, Choji; Harada, Yukari; Hosomi, Akira
Heterocycles, 1993 , vol. 35, # 1 p. 433 - 440
反应条件
tert.-butyl lithium
1.) THF, -70 deg C, 2.) decarboxylation; Yield given. Multistep reaction;
参考文献
Shapiro; Gomez-Lor
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5524 - 5526
反应条件
in acetonitrile
Rearrangement; ring cleavage; 1 h; Photolysis; Further byproducts given;
参考文献
Pavlik, James W.; Kebede, Naod
Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8325 - 8334
反应条件
calcium hydroxide powder; soda lime
bei der Destillation;
参考文献
Jowett
Journal of the Chemical Society, 1903 , vol. 83, p. 440,454
Journal of the Chemical Society, 1905 , vol. 87, p. 797
