2,4-二(三甲硅氧基)嘧啶合成路线 （共 49 条）
反应条件
trimethylsilyl trifluoromethanesulfonate in 1,2-dichloro-ethane T=83°C; 17 h; Product distribution / selectivity;
参考文献
Chou; Heath; Patterson; Poteet; Lakin; Hunt
Synthesis, 1992 , # 6 p. 565 - 570
反应条件
trimethylsilyl trifluoromethanesulfonate; [bis(acetoxy)iodo]benzene in dichloromethane T=20°C; 1 h;
参考文献
Yoshimura, Yuichi; Ohta, Masatoshi; Imahori, Tatsushi; Imamichi, Tomozumi; Takahata, Hiroki
Organic Letters, 2008 , vol. 10, # 16 p. 3449 - 3452
反应条件
trimethylsilyl trifluoromethanesulfonate; [bis(acetoxy)iodo]benzene in dichloromethane T=20°C; 15 h;
参考文献
Yoshimura, Yuichi; Ohta, Masatoshi; Imahori, Tatsushi; Imamichi, Tomozumi; Takahata, Hiroki
Organic Letters, 2008 , vol. 10, # 16 p. 3449 - 3452
反应条件
in acetonitrile T=60°C; 18 h;
参考文献
Dolman, Nigel P.; More, Julia C. A.; Alt, Andrew; Knauss, Jody L.; Troop, Helen M.; Bleakman, David; Collingridge, Graham L.; Jane, David E.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 8 p. 2579 - 2592
反应条件
1.) acetonitrile, 0 degC, 2.) 0 degC to R.T. 2 h; Yield given. Multistep reaction;
参考文献
Robins; Hatfield
Canadian Journal of Chemistry, 1982 , vol. 60, # 5 p. 547 - 553
反应条件
in N,N-dimethyl-formamide T=80 - 85°C; 24 h;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 7 p. 1211 - 1214
Zhurnal Organicheskoi Khimii, , vol. 28, # 7 p. 1527 - 1530
反应条件
trimethylsilyl trifluoromethanesulfonate in acetonitrile T=-40 - -30°C; 1.5 h;
参考文献
Archiv der Pharmazie, , vol. 324, # 2 p. 83 - 89
反应条件
trimethylsilyl trifluoromethanesulfonate in acetonitrile T=-10 - -5°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Lau; Pedersen; Jensen; Nielsen
Archiv der Pharmazie, 1991 , vol. 324, # 2 p. 83 - 89
反应条件
potassium carbonate in dichloromethane 24 h; Ambient temperature; Yield given;
参考文献
Pan; Chen; Piras; Dutschman; Rowe; Cheng; Chu -
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 1 p. 177 - 185
反应条件
tin(IV) chloride in 1,2-dichloro-ethane further catalysts: (CH3)3SiOSO2C4F9, (CH3)3SiClO4, (CH3)3SiOSO2CF3; Mechanism;
参考文献
Vorbrueggen, Helmut; Krolikiewicz, Konrad; Bennua, Baerbel
Chemische Berichte, 1981 , vol. 114, # 4 p. 1234 - 1255
