1: With sulfuric acid in methanol T=0 - 5°C; 2 h; 2: With formic acid; sulfuric acid; hydrogen; palladium on activated carbon in water P=4125.41 Torr; 24 h; 3: With sodium hydroxide in water T=10°C; 1.5 h;
1: With dimethylsulfide borane complex in 2-methyl tetrahydrofuran T=20 - 50°C; 2 h; 2: With hydrogenchloride; methanol; water in 2-methyl tetrahydrofuran T=5 - 20°C; 3: With potassium hydroxide in 2-methyl tetrahydrofuran; methanol; water T=50°C; Product distribution / selectivity;
1: in water T=20 - 75°C; 16 h; Industry scaleResolution of racemate; 2: With hydrogenchloride in water T=0 - 5°C; 3: With sodium hydroxide in water pH=~ 9 - ~ 10; Purification / work up;
