您好，欢迎来到魔法化学网！
| CAS号 : | 104632-26-0 |
精确质量 : | 211.11400 |
| 分子式 : | C10H17N3S |
logP : | 2.55430 |
| 分子量 : | 211.32700 |
PSA : | 79.18000 |
盐酸普拉克索 | |
pramipexole | |
104632-26-0 | |
C10H17N3S | |
211.32700 | |
79.18000 | |
2.55430 | |
211.11400 |
|
288-290°C
|
|
2934999090
|
|
|
3
|
|
|
R36/37/38
|
|
|
S26; S36
|
|
|
Xi
|
品名, 成分含量, 用途 |
|
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
|
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
2934999090. Other nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds. General tariff: |
|
|
0.02mol 2,6-二氨基-4,5,6,7-四氢苯并噻唑溶于34ml DMF,加入0.022mol正丙醛,在50℃加热1h。冷却,加入0.02mol硼氢化钠,在50℃加热30min。减压蒸出大部分溶剂,剩余物溶于20ml水,用2mol/L盐酸调至Ph值1。水层用乙酸乙酯萃取,萃取液和有机层丢弃。往水层中加入碳酸钾至碱性,然后用乙酸乙酯萃取,萃取液干燥,浓缩,加入含HCl的乙醚溶液,得到二盐酸普拉克索,收率42%,熔点286-288℃。 4-丙氨基环己酮(I)用氢溴酸在乙酸中溴化,生成物(Ⅱ)和硫脲缩合,再酸化即得二盐酸普拉克索。 | |
用于帕金森病的治疗。 |
